Vittoria Biotherapeutics, a clinical-stage immunotherapy company specializing in the development of innovative cell therapies for hard-to-treat diseases, today announced the successful completion of a $25 million private financing round. This funding is a $10 million extension to its previous $15 million financing secured in November 2023. The latest round was led by Valley Forge Investment Corporation, with new investments from the Global BioAccess Fund and Hatch Biofund, alongside ongoing support from existing investors Agent Capital, Tellus BioVentures, NYBC Ventures, and the University of Pennsylvania.
The funds will primarily support the company’s Phase 1 clinical trial of its lead oncology candidate, VIPER-101, an autologous, dual-population T cell therapy, as a potential treatment of T-cell Lymphoma. VIPER-101 leverages the company’s proprietary Senza5TM platform technology, which enhances T cell effector function by abrogating CD5-mediated immunosuppression through gene editing. The platform also features a rapid, five-day manufacturing process that significantly improves production efficiency while delivering enhanced functional benefits in preclinical testing. Senza5 has demonstrated outstanding preclinical anti-tumor efficacy across a range of liquid and solid tumor models. Vittoria’s broader pipeline includes novel assets targeting solid tumors and autoimmune diseases.